What is cinacalcet drug used for?
Cinacalcet is used to treat hyperparathyroidism in patients with chronic kidney disease who are on dialysis. Hyperparathyroidism is a condition that is caused when the parathyroid glands located in the neck make too much parathyroid hormone (PTH).
When is the best time to take cinacalcet?
It is best to take this medicine with food or shortly after a meal. Swallow the tablet whole. Do not crush, break, or chew it.
What are the main side effects of cinacalcet?
Common side effects of Sensipar include:
- nausea,
- vomiting,
- diarrhea,
- loss of appetite,
- muscle pain,
- mild chest pain,
- dizziness, or.
- weakness.
How quickly does cinacalcet work?
Clinical studies have shown that PTH response to cinacalcet is rapid, with nadir PTH concentration occurring approximately 3 hours after dosing; PTH concentrations remain suppressed at 24 hours as compared with baseline [12]. Cinacalcet half-life is about 6 hours and the terminal half-life ranges from 30 to 40 hours.
What are Calcimimetic drugs?
Calcimimetics (drugs that mimic the action of calcium on tissues) are a class of drugs used to treat hyperparathyroidism (a condition in which the parathyroid glands produce a high amount of parathyroid hormone [PTH]) in patients with chronic kidney disease (gradual loss of kidney function) who are being treated with …
Can you stop taking cinacalcet?
Cinacalcet may help control your condition but will not cure it. Continue to take cinacalcet even if you feel well. Do not stop taking cinacalcet without talking to your doctor.
How long can you live with hyperparathyroidism?
Here’s a sample from one site about the disorder: Parathyroid disease (hyperparathyroidism) causes symptoms in most people, but it will decrease the life expectancy in all patients by about 5-6 years if the parathyroid tumor is not removed … Most people with hyperparathyroidism don’t feel well.
Does cinacalcet cause high blood pressure?
This medicine may cause an increase or decrease in your blood pressure.
Can you just stop taking cinacalcet?
Your doctor will probably start you on a low dose of cinacalcet and gradually increase your dose, not more than once every 2-4 weeks. Cinacalcet may help control your condition but will not cure it. Continue to take cinacalcet even if you feel well. Do not stop taking cinacalcet without talking to your doctor.
What are calcimimetic drugs?
What is a calcimimetic and why is it prescribed?
What are the symptoms of hypoparathyroidism?
Signs and symptoms of hypoparathyroidism can include:
- Tingling or burning in your fingertips, toes and lips.
- Muscle aches or cramps in your legs, feet, stomach or face.
- Twitching or spasms of your muscles, particularly around your mouth, but also in your hands, arms and throat.
- Fatigue or weakness.
- Painful menstrual periods.
What is the molecular weight of cinacalcet?
Sensipar (cinacalcet) is a calcimimetic agent that increases the sensitivity of the calcium-sensing receptor to activation by extracellular calcium. Its empirical formula is C H F N•HCl with a molecular weight of 393.9 g/mol (hydrochloride salt) and 357.4 g/mol (free base). It has one chiral center having an R-absolute configuration.
What is the generic name for cinacalcet?
Generic name: cinacalcet (sin ah CAL set) Brand name: Sensipar Dosage forms: oral tablet (30 mg; 60 mg; 90 mg) Drug class: Calcimimetics
How many mg of cinacalcet HCI are in a RX tablet?
Sensipar (cinacalcet HCI) Tablets Rx Only 30 tablets 30 mg Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F).
What is cinacalcet used for?
What is cinacalcet? Cinacalcet decreases levels of parathyroid hormone (PTH), calcium, and phosphorous in the body. Cinacalcet is used to treat hyperparathyroidism (overactive functioning of the parathyroid glands) in people who are on long-term dialysis for kidney disease.