What is beta-2 GP1 IgG?
Beta-2 GP1 antibodies are found with increased frequency in patients with systemic rheumatic diseases, especially systemic lupus erythematosus. Beta-2 GP1 antibodies are detected in the clinical laboratory by different types of assays including immunoassays and functional coagulation assays.
What does antiphospholipid antibody positive mean?
High levels of this antibody may mean you have a higher risk for blood clots. Your healthcare provider can’t predict when a clot may happen. You may need a second test in about 12 weeks to confirm the results. A positive result doesn’t mean you need treatment.
What is beta-2 glycoprotein antibody test for?
Beta-2 glycoprotein 1 antibody tests are used alongside cardiolipin antibody and lupus anticoagulant testing to help diagnose the cause of unexplained blood clots (thrombotic episodes) or recurrent miscarriages, to help diagnose antiphospholipid syndrome (APS), or as part of the investigation of other autoimmune …
What is antiphospholipid antibody panel test for?
Antiphospholipid antibody testing is used to help determine the cause of: Inappropriate blood clot formation (unexplained thrombotic episode, excessive clotting) Recurrent miscarriage. Low platelet count (thrombocytopenia)
What is beta 2 gp1 IgM?
Beta-2-Glycoprotein 1 IgG/IgM test is an ELISA (Enzyme-linked immune sorbent assay) test that pits the IgG and IgM antibodies to fight against the beta-2-glycoprotein, present in serum and plasma.
What is beta-2 glycoprotein normal range?
Normal: β2 GPI IgG ≤ 20 SGU U/mL. β2 GPI IgM ≤ 20 SMU U/mL.
What does a high beta-2 glycoprotein mean?
A high level of beta-2 glycoprotein 1 antibody that is tested and confirmed as positive 12 weeks later means that it is likely that you have APS. This is especially true if other antiphospholipid antibody tests are positive.
When should antiphospholipid antibodies be tested?
Individuals with arterial thrombosis or unprovoked venous thrombosis before 50 years of age, recurrent thrombosis or thrombosis at an unusual site, or thrombotic microangiopathy of unknown etiology should be screened for antibodies associated with antiphospholipid syndrome.