What is hypericin?

Hypericin is an anthraquinone derivative that is naturally found in the yellow flower of Hypericum perforatum (St. John’s wort) with antidepressant, potential antiviral, antineoplastic and immunostimulating activities. Hypericin appears to inhibit the neuronal uptake of serotonin, norepinephrine, dopamine,…

What is the half life of hypericin?

The mean plasma elimination half-life of hypericin was 36.1±22.6 h for the 0.01 mg/kg dose level and 33.8±18.8 h for the 0.05 mg/kg dose level. The mean peak C max 28.1±11.8 ng/mL and the trough C min was 15.4±5.3 ng/mL.

What happens when hypericin enters the peripheral circulation?

When hypericin is absorbed by grazing animals and has entered the peripheral circulation the exposure to sunlight will cause severe sunburn and serious necrosis of the skin, followed by subsequent infection and starvation [6,203].

What is the CID number for hypericin?

Hypericin. PubChem CID. 3663. Structure. Find Similar Structures. Chemical Safety. Laboratory Chemical Safety Summary (LCSS) Datasheet. Molecular Formula. C30H16O8.