What is antiplatelet antibody test?

This blood test shows if you have antibodies against platelets in your blood. Platelets are a part of the blood that helps the blood clot.

Which assay is most commonly used to detect platelet antibody?

The most widely known and available tests are sandwich enzyme-linked immunosorbent assay (ELISA) methodologies using a microtiter plate coated with platelet glycoproteins (containing known platelet antigens) obtained from detergent lysates of antigen-typed platelets 14, 17.

What tests confirm ITP?

Diagnostic Procedures for ITP Includes a special blood test called an “anti-platelet antibody test.” Careful review of medications. Bone marrow aspiration: This test examines the platelet production and can rule out any abnormal cells the marrow may be producing that could lower platelet counts.

Is ITP and TTP the same?

Are ITP and TTP the same thing? No, ITP and TTP are not the same thing. Both ITP and TTP are bleeding disorders, but they occur for different reasons and may require different treatments.

Who diagnosis ITP?

To diagnose immune thrombocytopenia, your doctor is likely to order further blood tests that require drawing a small amount of blood from a vein in an arm. He or she may also refer you to a specialist in blood diseases (hematologist).

How do you interpret P2Y12 results?

180 – 376 PRU. Values less than 180 PRU may be evidence of a P2Y12 inhibitor effect. Platelet counts less than 119K or more than 502K, and Hematocrit values less than 33% or greater than 52% can interfere with testing and valid results may not be obtained.

What is a platelet-specific antibody test?

This is the primary test for detection of platelet-specific antibodies. It is not recommended for the diagnosis of immune thrombocytopenic purpura (ITP). This test will detect both allo and autoantibodies, but will not distinguish between them. Results of this test should be used in conjunction with clinical findings and other serological tests.

What is the sensitivity of platelet autoantibody testing?

The sensitivity of platelet autoantibody testing is low (53%). The specificity is high (> 90%). A positive autoantibody test can be useful to rule in ITP but a negative does not rule out ITP.

How to prepare for platelet antibodies test?

Platelet antibodies test looks after the platelet antibodies in the blood in order to find out the cause of low platelet count. As such no special preparation is needed for platelet antibodies test. Also, you do not need to fast. You can have your regular food and drink and the underlying medicines.

Does platelet platelet antibody test detect ITP?

Platelet Antibodies, Indirect. It is not recommended for the diagnosis of immune thrombocytopenic purpura (ITP). This test will detect both allo and autoantibodies, but will not distinguish between them. Results of this test should be used in conjunction with clinical findings and other serological tests.