What is diffuse Membranoproliferative glomerulonephritis?
Membranoproliferative glomerulonephritis (MPGN) is a form of glomerulonephritis caused by an abnormal immune response. Deposits of antibodies build up in a part of the kidneys called the glomerular basement membrane. This membrane helps filter wastes and extra fluids from the blood.
What is the difference between membranous glomerulonephritis and Membranoproliferative glomerulonephritis?
Membranoproliferative glomerulonephritis involves the basement membrane and mesangium, while membranous glomerulonephritis involves the basement membrane but not the mesangium. (Membranoproliferative glomerulonephritis has the alternate name “mesangiocapillary glomerulonephritis”, to emphasize its mesangial character.)
What is membranoproliferative glomerulonephritis (MPGN)?
Membranoproliferative glomerulonephritis (MPGN) type I. Immunofluorescent stained section. Intense, peripheral, glomerular, capillary loop deposition of immunoglobulin G (IgG) in an interrupted linear pattern corresponding to extensive subendothelial immune deposits (original magnification × 400).
What are the histopathologic findings of glomerulonephritis (MPGN)?
This entity refers to a pattern of glomerular injury based on the following three characteristic histopathologic findings: Membranoproliferative glomerulonephritis (MPGN) type I. Glomerulus with lobular accentuation from increased mesangial cellularity.
What is cryoglobulinemic glomerulonephritis (cdd’amico G)?
D’Amico G, Fornasieri A. Cryoglobulinemic glomerulonephritis: a membranoproliferative glomerulonephritis induced by hepatitis C virus. Am J Kidney Dis. 1995 Mar. 25 (3):361-9.
What is the pathophysiology of C3 glomerulonephritis?
C3 glomerulonephritis is similar in etiology to dense deposit disease, arising as a result of alternate complement activation or mutations in the complement-regulating proteins. C3NeF is commonly present. C3 glomerulonephritis has been associated with antifactor H activity and monoclonal gammopathies.