What is Nevoid hypopigmentation?
Abstract. Linear and whorled nevoid hypermelanosis (LWNH) is a rare disorder of pigmentation characterized by hyperpigmented macules in a linear or whorled streaky configuration. Lesions are distributed mainly on the trunk and extremities, sparing the palms, soles, and mucosae.
What is segmental pigmentation disorder?
Segmental pigmentation disorder (SegPD) is a rare type of cutaneous dyspigmentation. This hereditary disorder, first described some 20 years ago, is characterized by hypo and hyperpigmented patches on the trunk, extremities and less likely on the face and neck.
What causes pigmentary mosaicism?
Background. Pigmentary mosaicism is a term that describes varied patterns of pigmentation in the skin caused by genetic heterogeneity of the skin cells.
What is the difference between depigmentation and hypopigmentation?
While a decreased pigment production is reported as hypopigmentation, depigmentation has been defined as loss of pigment. In a similar way, partial lack of melanin is known as hypomelanosis while amelanosis is the total absence of melanin.
What is the difference between hypopigmentation and vitiligo?
Vitiligo is a common skin disease characterized by the presence of well circumscribed, depigmented milky white macules devoid of identifiable melanocytes. On the other hand, hypopigmented mycosis fungoides (MF) is a rare variant of MF which presents clinically as persistent hypopigmented macules and patches.
What causes skin depigmentation?
Depigmentation of the skin can be caused by a number of local and systemic conditions. The pigment loss can be partial (such as after injury to the skin) or complete (such as from vitiligo). It can be temporary (such as from tinea versicolor) or permanent (such as from albinism).
How do you treat depigmented skin?
Treatments
- Makeup or self-tanner. You can try applying a tinted cream to blend your affected facial skin with the rest of your complexion.
- Tattooing. Don’t think of this as a traditional tattoo that covers the depigmented skin.
- Medications.
- Light therapy.
- Skin grafts.
- Skin lighteners.
- Herbal supplements.
What is the difference between nevus and pigment lesion?
Pigmented lesions emerge and quickly develop into malignant melanoma within a few weeks after grafting on SCID mice (Chudnovsky et al., 2005). Nevus is a general term that may refer to any congenital lesion of various cell types or tissue types.
What is linear and whorled nevoid hypermelanosis?
Linear and whorled nevoid hypermelanosis (LWNHM) is a reticulate pigmentary disorder with a sporadic occurrence, representing genetic mosaicism. It is characterised by hyperpigmented macules in a reticulate pattern along Blaschko’s lines, sparing the mucous membranes and stabilising after one to two years.
What are pigmented lesions in gynecologic cancer?
Characteristic raised hyperkeratotic pigmented lesions are suggestive of carcinoma in situ and should be biopsied. A new term associated with pigmented lesions has emerged in gynecologic literature. Bowenoid papulosis is a variant of a pigmented lesion; dermatologists have noted this variant for some time.
What is the most common type of pigmented lesion?
The most common pigmented lesion is a lentigo, which is a concentration of melanocytes in the basal layer of cells. It can have the clinical appearance of a freckle, although it is more commonly confused with a nevus.