What is MDA MB 468 cell line?

MDA-MB-468 is a cell line with epithelial morphology that was isolated from a pleural effusion of a 51-year-old Black female patient with metastatic adenocarcinoma of the breast. These cells have applications in breast cancer and immuno-oncology research.

What kind of cells are MDA-MB-231?

The MDA-MB-231 cell line is an epithelial, human breast cancer cell line that was established from a pleural effusion of a 51-year-old caucasian female with a metastatic mammary adenocarcinoma1 and is one of the most commonly used breast cancer cell lines in medical research laboratories.

Is MDA-MB-231 a metastasis?

MDA-MB-231 cells develop primary tumors that produce spontaneous metastasis to lymph nodes and micrometastases to the lungs [4]. Detection of metastasis has relied primarily upon histological or PCR analysis of selected tissues at experimental end-points.

How long does it take MDA-MB-231 cells to adhere?

MDA-MB-231 adhesion to the microvessel wall. The initial adhesion time was 6.6 ± 0.8 (SE) min in 14 vessels. Figure 1 also demonstrates that, under ∼1 mm/s perfusion velocity, the mean blood flow velocity in this type of vessels, the cell adhesion increased linearly with the time during 60-min perfusion.

Are MCF 7 cells metastatic?

MCF-7 is a poorly-aggressive and non-invasive cell line (9), normally being considered to have low metastatic potential (8).

Are MCF7 cells tumorigenic?

In vivo, the MCF7. fgf-3 and MCF7. fgf-4 cells gave rise to tumors under conditions in which the control cells were not tumorigenic. Supplementing the mice with estrogen had the paradoxical effect of totally suppressing the start of the FGF-3 as well as the FGF-4 tumors.

What is the doubling time for MDA-MB-231?

Doubling time: 1.3 days (PubMed=9671407); 26.7 hours (PubMed=9815641); 24.7 hours (PubMed=24389870); 41.9 hours (NCI-DTP); 38 hours (ATCC); ~25-30 hours (DSMZ); ~38 hours (PBCF); 31.43 hours (https://www.synapse.org/#!Synapse:syn2347014).