Is clindamycin susceptible?

Clindamycin-susceptible, erythromycin-resistant Staphylococcus aureus (clindamycin-erythromycin discordant) may develop clindamycin resistance (7, 8). The erm gene product is a ribosome methylase whose expression is normally minimal.

Does clindamycin cause bacterial resistance?

When we use clindamycin alone topically, even in acne, it is more likely to cause bacterial resistance. However, when we combine clindamycin with benzoyl peroxide, the chance of resistance decreases significantly.

What does it mean to be resistant to clindamycin?

Inducible resistance to clindamycin was defined as blunting of the clear circular area of no growth around the clindamycin disk on the side adjacent to the erythromycin disk and was designated D-test positive.

Is Group B Strep susceptible to clindamycin?

According to Centers for Disease Control and Prevention reports published between 2006 and 2009, GBS resistance to clindamycin ranged from 13% to 20%, and resistance to erythromycin ranged from 25% to 32%.

Does clindamycin lose effectiveness?

USING ANTIBIOTICS All it does is increase the resistance of all the bacteria that happened to be sitting on the skin.” Topical clindamycin loses effectiveness after about two months unless it is combined with benzoyl peroxide, she explains.

What is clindamycin resistance?

How common is clindamycin resistance?

Among erythromycin-resistant strains, clindamycin resistance rates dropped from 22% to 10% over 4 years. Before being studied for the possibility of inducible clindamycin resistance, 90% of the strains appeared susceptible to clindamycin among CA-MRSA strains in 2002 (Table 1).

Is strep resistant to clindamycin?

Resistance of group B streptococcus (GBS) to antibiotics, particularly erythromycin and clindamycin, was studied. Erythromycin resistance was present in 22% of GBS isolates, and these isolates were constitutively resistant, inducibly resistant, or sensitive to clindamycin.