Are pleomorphic adenoma cancerous?

Although pleomorphic adenomas are benign parotid tumors, it has the potential to turn malignant. The incidence of malignant transformation increases with the duration of the tumor.

What is the most common site of pleomorphic adenoma?

Pleomorphic adenomas occur most often in the parotid gland, with a predilection for the tail of the superficial lobe (70-80% of cases). The tumor is less commonly seen in the submandibular gland (10%), and it is seldom encountered in the sublingual gland (1%).

What is the most appropriate treatment for a pleomorphic adenoma of the parotid?

The treatment of choice for pleomorphic adenomas is surgery, although there is the risk of damaging the nerve and causing a facial paresis. For surgically non resectable tumours, radiation therapy is widely used, which is also an effective adjuvant therapy.

Should pleomorphic adenoma be removed?

These are very aggressive tumors that are treated by radical parotid surgery followed by post-surgical chemotherapy and radiation therapy. Due to the aggressive nature of this tumor, and poor cure rate, it is advised that benign Pleomorphic adenomas be removed to prevent transformation into this cancer.

What is pleomorphic adenoma?

Key Takeaways 1 Pleomorphic adenoma is a benign tumor in the salivary gland. It is a firm and painless mass. 2 Around 70-80 percent of pleomorphic adenoma occur in the superficial lobe of the parotid gland,… 3 The primary cause of pleomorphic adenoma is a blockage in the salivary duct,…

How is pleomorphic adenoma of the salivary gland treated?

The surgical resection of the affected salivary gland is the mainstream management of pleomorphic adenoma. Complete excision or removal of the gland is recommended in the case of submandibular, sublingual, and minor salivary gland tumors.

What are the signs and symptoms of intraoral pleomorphic adenoma?

Intraoral pleomorphic adenoma happens when a tumor affects the minor salivary gland. In the case of large tumors, the following symptoms may be experienced: Pleomorphic adenoma develops as a lesion, which can slowly grow over the years. Manifestations usually occur depending on the primary location of the proliferating lesion.

What percentage of parotid adenomas are pleomorphic?

Around 70-80 percent of pleomorphic adenoma occur in the superficial lobe of the parotid gland, although the lesion may occur in any area of the parotid gland. Pleomorphic adenoma is less commonly seen in the submandibular salivary gland and is seldom observed in the sublingual gland.