How do you dissolve Treanda 100 mg?

100 mg Treanda for Injection vial: Add 20 mL of only Sterile Water for Injection, USP. Shake well to yield a clear, colorless to a pale yellow solution with a bendamustine HCl concentration of 5 mg/mL. The lyophilized powder should completely dissolve in 5 minutes.

What is the dosage for Treanda?

Treanda 1 Dosage Forms and Strengths. Treanda Injection: 45 mg/0.5 mL or 180 mg/2 mL as a clear and colorless to yellow ready-to dilute solution in a single-dose vial. 2 Contraindications. 3 Warnings and Precautions. 4 USE IN SPECIFIC POPULATIONS. 5 Treanda Description. 6 Treanda – Clinical Pharmacology.

How do I administer Treanda injection?

Each vial of Treanda Injection is intended for single dose only. Aseptically withdraw the volume needed for the required dose from the 90 mg/mL solution using a polypropylene syringe with a metal needle and a polypropylene hub. Immediately transfer the solution to a 500 mL infusion bag of 0.9% Sodium Chloride Injection, USP (normal saline).

How do you treat grade 3 Treanda?

Dose modifications for non-hematologic toxicity: for Grade 3 or greater toxicity, reduce the dose to 90 mg/m2 on Days 1 and 2 of each cycle; if Grade 3 or greater toxicity recurs, reduce the dose to 60 mg/m2 on Days 1 and 2 of each cycle. Preparation for Intravenous Administration. Treanda is a cytotoxic drug.

What CSTDs are not compatible with Treanda injection?

Most marketed CSTDs contain either polycarbonate or ABS and are not compatible with Treanda Injection (45 mg/0.5 mL or 180 mg/2 mL solution).

How is Treanda given?

Treanda is given as an infusion into a vein. A healthcare provider will give you this injection. Treanda is usually given for 2 days in a row every 21 to 28 days. You may receive up to 8 treatments total, depending on the condition being treated.

What are the different forms of Treanda?

Treanda is available in two formulations, a solution (Treanda Injection) and a lyophilized powder (Treanda for Injection).