What does arsenic do for leukemia?
Arsenic works by speeding up the death of leukaemic cells and encouraging normal blood cells to develop properly. It does this by working on particular proteins within the cell.
What is arsenic trioxide injection?
ARSENIC TRIOXIDE (AR se nik trye OX ide) is a chemotherapy drug. It slows the growth of cancer cells. This medicine is used to treat acute promyelocytic leukemia (APL). This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
How is arsenic trioxide administered?
Arsenic trioxide comes as a solution (liquid) to be injected into a vein by a doctor or nurse in a medical office or clinic. Arsenic trioxide is usually injected over 1 to 2 hours, but it may be injected over as long as 4 hours if side effects are experienced during the infusion.
What does arsenic oxide do to the body?
Ingesting (swallowing) high levels of inorganic arsenic can result in death. Lower levels of arsenic can cause nausea and vomiting, decreased red and white blood cells, abnormal heart rhythm, and numbness and tingling in the hands and feet. Organic arsenic compounds are less toxic than inorganic arsenic.
What are uses for arsenic?
Arsenic is used as a doping agent in semiconductors (gallium arsenide) for solid-state devices. It is also used in bronzing, pyrotechnics and for hardening shot. Arsenic compounds can be used to make special glass and preserve wood.
What is the chemical formula for arsenic trioxide?
As2O3Arsenic trioxide / Formula
Is arsenic trioxide toxic?
Arsenic trioxide (an odorless, tasteless, white or transparent, nonflammable solid) is one of the most toxic and prevalent forms of arsenic. The water solubility of arsenic salts varies depending on the salt. Arsenic trioxide is readily absorbed if ingested or inhaled, but only slowly absorbed through the skin.
Can arsenic trioxide help treat acute myeloid leukemia?
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of arsenic trioxide in treating patients who have acute myeloid leukemia.
What is arsenic trioxide (ATO)?
Arsenic trioxide (ATO) is very potent as a single agent against acute promyelocytic leukemia (APL). This old drug was reintroduced into new medicine by Chinese studies on APL treatment and rapidly approved by the FDA for relapsed cases.
How is acute promyelocytic leukemia (APL) treated?
An efficient therapeutic approach to patients with acute promyelocytic leukemia using a combination of arsenic trioxide with low-dose all-trans retinoic acid. Hematological oncology. 2004;22(2):63–71.
How effective is amoxicillin for acute promyelocytic leukemia?
It has been demonstrated that this drug is effective against all stages of acute promyelocytic leukemia, including for remission induction of relapsed cases, or as first-line treatment. It is also useful in the consolidation/maintenance phase of treatment.
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