What is diffuse adenomyomatosis?

Adenomyomatosis is a rare benign proliferative disease of the gallbladder characterized by epithelial proliferation and formation of mucosal pouches through the thickened muscular layer of gall bladder wall.

What is adenomyomatosis of gallbladder wall?

Gallbladder adenomyomatosis (GA) is a benign alteration of the gallbladder wall that can be found in up to 9% of patients. GA is characterized by a gallbladder wall thickening containing small bile-filled cystic spaces (i.e., the Rokitansky–Aschoff sinuses, RAS).

What is diffuse gallbladder?

Diffuse gallbladder wall thickening may be caused by a wide range of gallbladder diseases and extracholecystic pathologic conditions. In most cases its cause can be determined by correlation of the clinical presentation and associated imaging findings.

What causes Adenomyomatosis of the gallbladder?

It occurs as a result of poorly understood hyperplastic changes involving the mucosa and muscular wall of the gallbladder and the formation of intramural sinuses, known as the Rokitansky-Aschoff sinuses, which are characteristic of this disease. Involvement of the gallbladder may be diffuse or segmental.

Does Adenomyomatosis of the gallbladder require surgery?

Symptomatic adenomyomatosis is considered an indication for cholecystectomy, while asymptomatic disease is not an indication for surgery. If there is any clinical or radiological doubt about the possibility of adenocarcinoma of the gallbladder, a cholecystectomy is usually warranted [7].

What is diffuse gallbladder wall thickening?

Conclusion: Diffuse gallbladder wall thickening may be caused by a wide range of gallbladder diseases and extracholecystic pathologic conditions. In most cases its cause can be determined by correlation of the clinical presentation and associated imaging findings.

What is the difference between adenomyosis and adenomyomatosis?

Adenomyomatosis is characterized by enlarged Rokitansky–Aschoff sinuses and thickening of the muscularis layer of the gallbladder. As a result, adenomyomatosis (which should not be confused with adenomyosis, a condition that affects the uterus) manifests as gallbladder wall thickening with intramural cystic spaces.

What is the treatment for gallbladder adenomyomatosis?