Can hydralazine cause fever?
Symptoms may occur anywhere from three weeks to two years after taking hydralazine and include rash, fever, weight loss, fatigue, joint or muscle pain, and kidney inflammation. Seek urgent medical advice if this occurs.
What is the side effect of hydralazine?
Headache, pounding/fast heartbeat, loss of appetite, nausea, vomiting, diarrhea, or dizziness may occur as your body adjusts to the medication. If any of these effects last or get worse, tell your doctor or pharmacist promptly. To reduce the risk of dizziness, get up slowly when rising from a sitting or lying position.
What are the contraindications of hydralazine?
Who should not take HYDRALAZINE HCL?
- heart attack within the last 30 days.
- coronary artery disease.
- a stroke.
- low blood pressure.
- a condition with symptoms that resemble lupus.
- high pressure within the skull.
- decreased blood volume.
- slow acetylator.
Is there a black box warning for hydralazine?
Warnings. In a few patients Hydralazine may produce a clinical picture simulating systemic lupus erythematosus including glomerulonephritis. In such patients Hydralazine should be discontinued unless the benefit-to- risk determination requires continued antihypertensive therapy with this drug.
Can hydralazine cause chills?
Hypersensitive Reactions: rash, urticaria, pruritus, fever, chills, arthralgia, eosinophilia, and, rarely, hepatitis. Other: nasal congestion, flushing, lacrimation, conjunctivitis.
Can hydralazine cause hyponatremia?
Metabolic alkalosis, hyponatremia, hypomagnesemia, hypercalcemia, hyperglycemia, and elevated serum uric acid levels are also relatively common.
What is the antidote for hydralazine?
The signs and symptoms of hydralazine overdose include hypotension, tachycardia, headache and generalised skin flushing. Complications can include myocardial ischemia and subsequent myocardial infarction, cardiac arrhythmias, profound shock and coma. There is no specific antidote.
How does hydralazine metabolize in the body?
Hydralazine undergoes extensive hepatic metabolism; it is excreted mainly in the form of metabolites in the urine. Patients should be informed of possible side effects and advised to take the medication regularly and continuously as directed.
Can hydralazine cause night sweats?
tamoxifen (Nolvadex), hydralazine (Apresoline), nitroglycerine, and sildenafil (Viagra). Many other drugs not mentioned above, including cortisone medications, such as prednisone and prednisolone, may also be associated with flushing or night sweats.
Can allopurinol cause hyperkalemia?
Hypercalcemia, hypocalcemia, hyperphosphatemia, hypokalemia, hyperuricemia, electrolyte abnormality, hyperglycemia, hypernatremia, metabolic acidosis, glycosuria, hyperkalemia, lactic acidosis, water intoxication, and hypomagnesemia have been reported in less than 1% of patients.
What drugs cause hyponatraemia?
Opioids.
How is hydralazine excreted?
What are the side effects of hydralazine?
Hydralazine has been reported to cause headaches, nausea, flushing, hypotension, palpitations, tachycardia, dizziness, and angina. [11] Immune phenomena such as drug-induced lupus erythematosus (DILE), serum sickness, hemolytic anemia, vasculitis, and glomerulonephritis have been reported using hydralazine.
What is hydralazine/hydrochlorothiazide?
Hydralazine/hydrochlorothiazide is a fixed-combination tablet that combines a vasodilator, hydralazine and a thiazide diuretic, hydrochlorothiazide Hydralazine, a direct vasodilator, dilates arterioles with little effect on veins; decreases systemic resistance
How does hydralazine work to lower blood pressure?
Medically reviewed by Drugs.com on Jan 10, 2018 – Written by Cerner Multum. Hydralazine is a vasodilator that works by relaxing the muscles in your blood vessels to help them dilate (widen). This lowers blood pressure and allows blood to flow more easily through your veins and arteries.
What is the generic name for hydralazine (Hye DRAL)?
Generic Name: hydralazine (hye DRAL a zeen) Brand Name: Apresoline. Dosage Forms: oral tablet (10 mg; 100 mg; 25 mg; 50 mg) Medically reviewed by Drugs.com on Dec 31, 2020. Written by Cerner Multum. Uses. Warnings. Dosage. What to avoid.