Does CMV cause hepatosplenomegaly?

The first described case of CMV hepatitis involved a child with chorioretinitis, hepatosplenomegaly, and cerebral calcifications. Hepatitis has been commonly observed in patients with primary CMV infection and mononucleosis.

Can cytomegalovirus affect the liver?

Liver damage is a characteristic feature of the clinical syndromes caused by cyto- megalovirus (CMV) infection in man. Jaundice and hepatosplenomegaly occur commonly in cytomegalic inclusion dis- ease of the newborn.

What are the most common laboratory findings in CMV infection in the newborn?

Typical clinical symptoms of congenital CMV infection that are found in infected neonates include intrauterine growth retardation, microcephaly with intracranial calcification, hepatosplenomegaly, jaundice, chorioretinitis, thrombocytopenic purpura and anemia.

What are the congenital abnormalities associated with CMV infection?

Some babies with signs of congenital CMV infection at birth may have long-term health problems, such as: Hearing loss. Developmental and motor delay. Vision loss.

What type of doctor treats cytomegalovirus?

Infectious disease experts should be consulted to help treat CMV infection and to help exclude underlying human immunodeficiency virus (HIV) infection.

What is CMV virus in infants?

What is CMV in newborns? CMV (cytomegalovirus) is a herpes virus. It’s very common. It affects people of all ages and in all parts of the U.S. In most cases, CMV causes mild symptoms, or no symptoms at all. But it can cause serious problems in an unborn baby or newborn.

Does CMV retinitis go away?

Treatment and Prognosis. Up to 95% of people with CMV retinitis do well with treatment. Antiviral medications include cidofovir (Vistide), foscarnet (Foscavir), and valganciclovir (Valcyte).

Can CMV be cured in babies?

Newborns may develop neurologic problems such as hearing loss. Handwashing can help prevent spread of the virus. Cytomegalovirus infection cannot be cured, but some antiviral drugs can limit the problems caused by infection.

Can babies recover from CMV?

Most babies with congenital CMV have no symptoms. CMV can cause serious problems in the unborn baby and newborn. Some newborns with CMV may be treated with antiviral medicine. Washing hands with soap and water works well to remove the virus from the hands to prevent spreading CMV.

What happens if a baby is born with cytomegalovirus?

Babies Born with Congenital Cytomegalovirus (CMV) When a baby is born with cytomegalovirus (CMV) infection, it is called congenital CMV. Most babies with congenital CMV never show signs or have health problems. However, some babies have health problems at birth or that develop later.

Can congenital cytomegalovirus cause hearing loss in babies?

Some babies without signs of congenital CMV infection at birth may have hearing loss. Hearing loss may be present at birth or may develop later, even in babies who passed the newborn hearing test. A pregnant woman can pass CMV to her unborn baby.

How is congenital cytomegalovirus (CMV) infection treated?

Treatment and Management. For babies with signs of congenital CMV infection at birth, antiviral medications, primarily valganciclovir, may improve hearing and developmental outcomes. Valganciclovir can have serious side. effects and has only been studied in babies with signs of congenital CMV infection.

How is congenital cytomegalovirus diagnosed?

Diagnosis Congenital CMV infection can be diagnosed by testing a newborn baby’s saliva, urine (preferred specimens), or blood. These specimens must be collected for testing within two to three weeks after the baby is born in order to confirm a diagnosis of congenital CMV infection.