Is zimelidine a pyridylallylamine?

Zimelidine ( INN, BAN) (brand names Zimeldine, Normud, Zelmid) was one of the first selective serotonin reuptake inhibitor (SSRI) antidepressants to be marketed. It is a pyridylallylamine, and is structurally different from other antidepressants.

When was zimelidine first used?

Zimelidine was developed in the late 1970s and early 1980s by Arvid Carlsson, who was then working for the Swedish company Astra AB. It was discovered following a search for drugs with structures similar to brompheniramine (it is a derivative of brompheniramine), an antihistamine with antidepressant activity. Zimelidine was first sold in 1982.

How safe is zimelidine?

While zimelidine had a very favorable safety profile, within a year and a half of its introduction, rare case reports of Guillain–Barré syndrome emerged that appeared to be caused by the drug, prompting its manufacturer to withdraw it from the market.

What is cimetidine?

or pronounce in different accent or variation? It is a drug that is used for treating gastroesophageal reflux disease and Zollinger-Ellison syndrome. Learn more about the word “cimetidine” , its origin, alternative forms, and usage from Wiktionary.