What are Nalm 6 cells?

What are Nalm 6 cells?

Nalm6 is a B cell precursor leukemia cell line initiated from an adolescent male. It is a CD24-positive xenograft model of acute lymphoblastic leukemia.

What are Reh cells?

Reh is a human cell line exhibiting lymphoblastic morphology that was isolated from tissue from an acute lymphocytic leukemia (ALL) patient. It was desposited by the University of Pennsylvania. Use these cells in your immune system disorder and cancer research.

Is Jurkat a CD4?

Jurkat is a CD4 T cell line provided by O. Acuto (Institut Pasteur, Paris, France). Kit 225 is a CD4 T cell line expressing high- and intermediate-affinity IL-2R (13). YT is a cell line expressing intermediate-affinity IL-2R.

Do Jurkat cells express CD8?

Both α′β′CD8 and “α′β′CD8” Jurkat cells expressed similar CD8 levels (Supplemental Fig. 1A).

Do Jurkat cells express CD3?

Jurkat clones express different levels of CD3 antigen: low on 217.6 clone (A), high on 217.9 (B) and ranging from low to high levels on clone 217.7 (C).

Is Jurkat CD4 or CD8?

Jurkat is a CD4+/CD8- T-cell lymphoma that expresses an endogenous TCR. The T2 line is a TAP-deficient T-cell/B-cell hybridoma expressing HLA-A2.

Are Jurkat cells CD4 or CD8?

HLA-A2 negative tumor cell lines included RCC 1764, MEL 586 and MEL 624-28. Jurkat is a CD4+/CD8- T-cell lymphoma that expresses an endogenous TCR. The T2 line is a TAP-deficient T-cell/B-cell hybridoma expressing HLA-A2.

What is the Nalm6 cell line used for?

Nalm6 cells are great models for B-cell differentiation, CNS infiltration and metastasis, as well as pre-B leukemias [1-3]. As a CD19+ cell line, traceable Nalm6 cells are ideal for testing novel CAR T cell or other immunotherapies for efficacy in vivo [4].

What is the Leibniz Institute DSMZ?

Welcome to the Leibniz Institute DSMZ. German Collection of Microorganisms and Cell Cultures GmbH. Research. The research focus of the almost 100 scientists at the DSMZ are the various aspects of biodiversity in prokaryotes & eukaryotes.

What is the research focus at DSMZ?

The research focus of the almost 100 scientists at the DSMZ are the various aspects of biodiversity in prokaryotes & eukaryotes. In our online shop we offer the most diverse portfolio of bioresources for researchers from academia & industry.

Where do Nalm6 cells metastasize to?

Depending on the route of inoculation (see below), implanted Nalm6 cells can metastasize to the bone marrow, liver, spleen, and lymph nodes. The following chart provides some examples of Nalm6 cells used for tumor formation and studies.