What class of drug is methenamine?

Methenamine belongs to the family of medicines called anti-infectives. It is used to help prevent and treat infections of the urinary tract. Methenamine is available only with your doctor’s prescription.

What ingredients are in methenamine?

The active substance is methenamine hippurate. Each tablet contains 1 gram. The other ingredients are magnesium stearate (E572), povidone and colloidal anhydrous silica.

Is methenamine an acid?

Methenamine Hippurate is the hippurate salt form of methenamine, a prodrug and inactive weak base that slowly hydrolyzes in acidic urine to ammonia and the effective, urinary tract antiseptic formaldehyde.

What is another name for methenamine?

BRAND NAME(S): Hiprex, Mandelamine, Urex. USES: Methenamine is used to prevent or control returning urinary tract infections caused by certain bacteria. It is not used to treat an active infection. Other antibiotics must be used first to treat and cure the infection.

Is methenamine a safe drug?

Many people using this medication do not have serious side effects. Taking higher than recommended doses of methenamine may cause bladder irritation, painful/frequent urination, and bloody/pink urine. Tell your doctor right away if you have any of these symptoms.

What bacteria does methenamine treat?

When the urine is acidic, methenamine turns into formaldehyde to kill the bacteria. This drug is effective only against bacterial infections in the urinary tract. It will not work for other types of bacterial infections (such as in the blood) or for viral infections (such as the common cold or flu).

Is methenamine an antibiotic?

Methenamine, an antibiotic, eliminates bacteria that cause urinary tract infections. It usually is used on a long-term basis to treat chronic infections and to prevent recurrence of infections. Antibiotics will not work for colds, flu, or other viral infections.

Is methenamine an antiseptic?

Methenamine works as an antiseptic, which does not pose a risk of organisms developing resistance. In an acidic environment, methenamine is hydrolyzed to ammonia and formaldehyde.

How effective is methenamine?

A Cochrane systematic review that included 13 studies and a total of 2032 patients found that methenamine was effective for UTI prophylaxis in patients without renal tract abnormalities (symptomatic UTI: RR = 0.24, 95% CI = 0.07 to 0.89; bacteriuria: relative risk (RR) = 0.56, 95% CI = 0.37 to 0.83).

What are the side effects of methenamine?

Nausea, vomiting, diarrhea, abdominal cramps, and loss of appetite may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Painful or difficult urination may occur with methenamine, although less often.

What is the molecular weight of methenamine?

Methenamine PubChem CID 4101 Synonyms methenamine Hexamethylenetetramine 100-9 Molecular Weight 140.19 Date s Modify 2021-07-03 Create 2005-03-25

What is the LCSs formula for methenamine?

Laboratory Chemical Safety Summary (LCSS) Datasheet. Molecular Formula. C15H21N5O3. Synonyms. Methenamine hippurate. 5714-73-8. Hiprex. Hippramine. Haiprex.

What is the formula for methenamine hippurate?

Methenamine hippurate is a N-acylglycine. It derives from a N-benzoylglycine. InChI=1S/C9H9NO3.C6H12N4/c11-8 (12)6-10-9 (13)7-4-2-1-3-5-7;1-7-2-9-4-8 (1)5-10 (3-7)6-9/h1-5H,6H2, (H,10,13) (H,11,12);1-6H2

What is the brand name for methenamine?

Multi-ingredient medications containing methenamine: benzoic acid/hyoscyamine/methenamine/methylene blue/phenyl salicylate systemic. Brand names: Hyophen, Prosed DS, Methylphen, Urophen MB. Drug class(es): urinary antispasmodics.