What does it mean when a cancer is refractory?

Listen to pronunciation. (reh-FRAK-tor-ee KAN-ser) Cancer that does not respond to treatment. The cancer may be resistant at the beginning of treatment or it may become resistant during treatment.

What does it mean when symptoms are refractory?

A refractory symptom is one that cannot be adequately controlled despite aggressive efforts to identify a tolerable therapy that does not compromise consciousness (Cherny 1994). A refractory symptom may be subjective and, at times, nonspecific.

What is refractoriness in pharmacology?

Medical Definition of refractoriness : the insensitivity to further immediate stimulation that develops in irritable and especially nervous tissue as a result of intense or prolonged stimulation.

What is refractory non Hodgkins?

Refractory non-Hodgkin lymphoma (NHL) is NHL that has not responded to initial treatment. Refractory disease may be disease that is getting worse or staying the same. Relapsed non-Hodgkin lymphoma (NHL) is NHL that responded to treatment but then returns.

What is refractory in cancer treatment?

The word “refractory” in general use means stubborn or intractable, and in medicine it is specifically applied to disease that does not respond to treatment. Refractory cancer refers to cancer that may be resistant at the beginning of treatment, or becomes resistant during treatment.

What are refractory symptoms in heart failure?

Refractory CHF is defined as symptoms of CHF at rest or repeated exacerbations of CHF despite “optimal” triple-drug therapy. Most patients with refractory CHF require hemodynamic monitoring and treatment in the intensive care unit.

What is refractory period of heart?

The effective refractory period (ERP) is the longest premature coupling interval (S1-S2) at a designated stimulus amplitude (usually 2× diastolic threshold) that results in failure of propagation of the premature impulse through a tissue.

What does Refractable mean?

Capable of being refracted
Adjective. refractable (not comparable) Capable of being refracted.

What happens if you don’t treat non-Hodgkin’s lymphoma?

If left untreated, the disease will lead to death. If you decline life-saving treatment, you can choose to get support from palliative care (a medical team that manages your symptoms and pain).

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