What is dexamethasone?

What is dexamethasone?

Dexamethasone is a synthetic pregnane corticosteroid and derivative of cortisol (hydrocortisone) and is also known as 1-dehydro-9α-fluoro-16α-methylhydrocortisone or as 9α-fluoro-11β,17α,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione. The molecular and crystal structure of dexamethasone has been determined by X-ray crystallography.

What is a substitute for dexamethasone 6 mg IV?

Remark: Dexamethasone 6 mg IV or PO for 10 days (or until discharge if earlier) or equivalent glucocorticoid dose may be substituted if dexamethasone unavailable. Equivalent total daily doses of alternative glucocorticoids to dexamethasone 6 mg daily are methylprednisolone 32 mg and prednisone 40 mg. Recommendation 5.

What drugs can interact with dexamethasone?

Many drugs can interact with dexamethasone, especially: NSAIDs (non-steroidal anti-inflammatory drugs) – aspirin, ibuprofen ( Advil, Motrin ), naproxen ( Aleve ), celecoxib, diclofenac, indomethacin, meloxicam, and others. This list is not complete and many other drugs may affect dexamethasone.

How many mg of Dexamethasone should I take with bortezomib?

-In regimens containing bortezomib, the day 1 dexamethasone dose may be split to provide 20 mg on the day of and 20 mg on the day after bortezomib. -Doses may need to be adjusted for performance status or other toxicities Use: For the treatment of multiple myeloma. Usual Adult Dose for Multiple Sclerosis

Common conditions treated include asthma, allergies, and arthritis. It is also used for other conditions, such as blood disorders and diseases of the adrenal glands. The lowest GoodRx price for the most common version of dexamethasone is around $7.59, 82% off the average retail price of $44.51.

How much does dexamethasone cost?

Generic dexamethasone is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. The lowest GoodRx price for the most common version of dexamethasone is around $7.59, 83% off the average retail price of $47.01. Compare corticosteroids.

How many mg of dexamethasone can you take in a day?

-Studies have shown dexamethasone in single doses (0.3 mg/kg up to 1.7 mg/kg; maximum single dose 36 mg) or multiple doses (0.6 mg/kg once a day for 2 days) is comparable to a 5-day course of prednisone/prednisolone in the treatment of acute asthma exacerbations.

How effective is dexamethasone for nerve pain?

Dexamethasone 0.5 MG Tablet essentially treats nerve pain like trigeminal neuralgia as well as diabetic neuropathy. Moreover, the drug also effectively treats bipolar disorder. Dexamethasone 0.5 MG Tablet functions as an anticonvulsant and decreases the occurrence of abnormal nerve impulses in the brain which can lead to severe reactions like

NCI Thesaurus (NCIt) Dexamethasone is a fluorinated steroid that is 9-fluoropregna-1,4-diene substituted by hydroxy groups at positions 11, 17 and 21, a methyl group at position 16 and oxo groups at positions 3 and 20. It is a synthetic member of the class of glucocorticoids.

How long do the effects of dexamethasone last?

The effects of dexamethasone are frequently seen within a day and last for about three days. The long-term use of dexamethasone may result in thrush, bone loss, cataracts, easy bruising, or muscle weakness.

Is it possible to take dexamethasone with phenytoin?

Berikut ini beberapa interaksi antarobat yang dapat terjadi apabila dexamethasone digunakan bersamaan dengan obat lain: Penurunan kadar dexamethasone di dalam darah jika digunakan bersama phenytoin, rifampicin, barbiturat, carbamazepine, atau ephedrine