What is phenytoin 100mg used for?
Phenytoin is used to control certain type of seizures, and to treat and prevent seizures that may begin during or after surgery to the brain or nervous system. Phenytoin is in a class of medications called anticonvulsants.
What are phenytoin sodium tablets used for?
Phenytoin Sodium Flynn Hard Capsules are indicated for control of tonic-clonic seizures (grand mal epilepsy), partial seizures (focal including temporal lobe) or a combination of these, and for the prevention and treatment of seizures occurring during or following neurosurgery and/or severe head injury.
What are the side effects of phenytoin?
Headache, nausea, vomiting, constipation, dizziness, feeling of spinning, drowsiness, trouble sleeping, or nervousness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Phenytoin may cause swelling and bleeding of the gums.
When should phenytoin levels be taken?
A level can be taken 2-4 hours following an IV loading or top-up dose (12-24 hours for oral doses) and levels should then be monitored every 24 hours until control is achieved and concentration has stabilised.
What causes epilepsy?
When epilepsy is diagnosed in older adults, it’s sometimes from another neurological issue, like a stroke or a brain tumor. Other causes can be related to genetic abnormalities, prior brain infection, prenatal injuries or developmental disorders. But in about half of people with epilepsy, there’s no apparent cause.
What type of seizure is phenytoin used for?
Phenytoin is best used for partial-onset seizures. It generally is not effective against generalized-onset absence seizures or infantile spasms. It has limited value in clonic, myoclonic, and atonic seizures and in the Lennox-Gastaut syndrome. It may control the tonic-clonic component of the syndrome.
Who should not take phenytoin?
systemic lupus erythematosus, an autoimmune disease. decreased calcification or density of bone. a body temperature higher than 101 degrees Fahrenheit. swollen lymph nodes.
What do phenytoin levels indicate?
Toxic phenytoin levels are defined as greater than 30 µg/mL. Lethal levels are defined as greater than 100 µg/mL. The reference range of free phenytoin is 1-2.5 µg/mL. In patients with renal failure associated with hypoalbuminemia, free phenytoin levels may be more accurate than total phenytoin levels.
What causes low phenytoin levels?
Drugs that may reduce phenytoin blood levels include antiepileptic drugs (e.g., carbamazepine), antiviral agents (e.g., fosamprenavir, ritonavir), others (e.g., diazepam, rifampin, theophylline) and chronic alcohol abuse.