What type of cell is MCF-7?

MCF-7 is a human breast cancer cell line with estrogen, progesterone and glucocorticoid receptors [26]. It is derived from the pleural effusion of a 69-year-old Caucasian metastatic breast cancer (adenocarcinoma) in 1970 by Dr Soule of the Michigan Cancer Foundation, Detroit, MI [27].

What is HCC1806 cell line?

HCC1806 is an epithelial cell line isolated from the mammary gland of a 60-year-old, Black, female patient with acantholytic squamous cell carcinoma (ASCC), TNM Stage IIB, grade 2. The HCC1806 breast cancer cell line was initiated in 1995 and took 10 months to establish.

What are MCF-7 cells used for?

MCF-7 cells are used ubiquitously in research for ER-positive breast cancer cell experiments, with the majority of the investigations into acquired anti-estrogen drug resistance having utilized them.

What is cell line?

Cell Line. A cell line is a permanently established cell culture that will proliferate indefinitely given appropriate fresh medium and space. Lines differ from cell strains in that they become immortalized.

What are cell lines used for?

Cell lines have revolutionized scientific research and are being used in vaccine production, testing drug metabolism and cytotoxicity, antibody production, study of gene function, generation of artificial tissues (e.g., artificial skin) and synthesis of biological compounds e.g., therapeutic proteins.

What is Acantholytic squamous cell carcinoma?

Adenoid (acantholytic) squamous cell carcinoma (ASCC) is a histological variant of squamous cell carcinoma which occurs mainly in the sun-exposed areas of the head and neck region. It is commonly seen among males which mainly occurs in the sixth and seventh decade of life with lip being predominately affected.

What is bt474 cell line?

BT-474 is a cell line exhibiting epithelial morphology that was isolated from a solid, invasive ductal carcinoma of the breast obtained from a 60-year-old, White, female breast cancer patient. Use these cells in your cancer research.

What is infiltrating ductal carcinoma?

Invasive ductal carcinoma (IDC), also called infiltrating ductal carcinoma, is the most common type of breast cancer. About 80% of all breast cancers are IDC, according to the American Cancer Society. Advertisement. Invasive means the cancer has spread into surrounding breast tissues.

Why use authenticated ATCC cells?

To ensure your research is high quality, use authenticated ATCC cells. ATCC has the world’s largest and most extensive product catalog of human and animal cell lines for research purposes. The cell biology collection includes more than 4,000 continuous cell lines available by species, tissue/disease types, and signaling pathways.

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What are ATCC hTERT-immortalized primary cells?

ATCC hTERT-immortalized primary cells also display normal in vivo biologies but have the added advantages of high proliferative capability, and the ability to be used at high passage.

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