What is curettage and bone grafting?

The curettage process activates the bone matrix which helps regenerate bone in the defect. Large bone defects may be reinforced with bone substitutes such as bone cement, bone grafts obtained from your body or an implant. Curettage also helps the bone integrate and fuse with a graft or implant.

What is curettage and cementation?

Curettage with cement augmentation involves thorough curettage of a pathological lesion from the bone and filling the residual cavity with polymethyl methacrylate (PMMA). It is particularly useful for giant cell tumors that extend to the subchondral area but do not usually invade the cartilage.

What is the best treatment for giant cell tumor?

Surgery has proven to be the most effective treatment for giant cell tumors. Surgical treatment may include: Curettage. Curettage is the surgical procedure most commonly used to treat giant cell tumors.

Does giant cell tumor cause bone resorption?

Giant cell tumour of bone (GCTB) is a locally aggressive RANK ligand dependent bone tumour causing lacunar bone resorption.

Is curettage the same as excision?

One half is treated by curettage, the other half by surgical excision. The follow-up period is four years. If the difference between recurrence rates is ≤7% and the cosmetic outcome as well as the surgery-related complications are not worse after curettage, surgical excision must be considered an overtreatment.

What is the survival rate for chondrosarcoma?

The 5-year survival rate for chondrosarcoma is 75.2%, which is much higher than that of osteosarcoma and Ewing sarcoma 3. Tumor size, grade, stage, local recurrence, metastasis at presentation, systemic treatment, and radiotherapy are all associated with the prognosis of chondrosarcoma 4-7.

Is a giant cell tumor malignant?

Most giant cell tumors occur at the ends of the long bones of the arms and legs, near a joint (such as the knee, wrist, hip, or shoulder). Most are benign (not cancer) but some are malignant (cancer). Giant cell tumors usually occur in young and middle-aged adults. Also called GCT.

Can giant cell tumor recur?

Clinically, GCT presents as a benign but often aggressive lesion with a tendency toward local recurrence. Depending on the type of treatment and the local presentation of the tumor, recurrence rates range from 0% to 65% (Table 1) [1, 3, 5, 6, 15, 20, 25, 26, 29, 31, 37, 38, 40, 43, 50].

Is Osteoclastoma malignant?

The giant cell tumor of bone (GCTB), also known as an osteoclastoma or a myeloid sarcoma, is a benign local aggressive osteolytic neoplasm that primarily affects skeletally mature young adults.

What is a giant cell tumor of bone?

Giant cell tumor (GCT) of bone is one of the commonest benign bone tumors encountered by an orthopedic surgeon.

Does subchondral bone integrity affect the outcome of giant cell tumors?

Giant cell tumors of the knee: Subchondral bone integrity affects the outcome. Int Orthop. 2005;29:30–4. [PMC free article][PubMed] [Google Scholar]

What is the recurrence rate of giant cell tumors?

The local recurrence rate of giant cell tumors confined to bone (Campanacci Grades I and II) was only 7% compared with 29% in tumors with extraosseous extension (Campanacci Grade III).

What is the role of phenol in the treatment of giant cell tumors?

Phenol as an adjuvant for local control in the treatment of giant cell tumor of the bone. Eur J Surg Oncol. 1999;25:610–8. [PubMed] [Google Scholar]